Spectrum of Hepatic Pathologies in Medicolegal Autopsies
Keywords:Autopsy, Histopathology, Liver disease, Cirrhosis
Background: Silent liver disease is a major cause of morbidity and mortality in the population due to its silent
progression to end stage liver disease without significant symptoms. We aim to study pattern of pathological
findings and latent forms of diseases in the 100 liver autopsy specimen and to find clinicopathological
correlation between clinical diagnosis and pathological diagnosis wherever possible.
Method: The present study was conducted on 100 liver autopsy specimens received in the department of
Pathology, Govt. Medical College, Patiala. Sections from representative areas were submitted for processing,
sectioned and stained with Hematoxylin & Eosin stain.
Results: Out of 100 specimens, 38 cases (38%) showed hepatic steatosis, followed by cirrhosis 14
cases(14%), chronic venous congestion 13 (13%) cases, portal triaditis 12 (12%) cases, normal 12 (12%)
cases , hepatitis 8 (8%) cases , granulomatous/ tuberculosis pathology 2 (2%) cases and 1(1%)metastatic
deposits of carcinoid tumour. Maximum cases seen in age group of 41-50 years with mean age 39.92±12.68
years. Liver disease predominated in males with male:female ratio of 6:1.
Conclusion: Silent liver diseases are not uncommon. Autopsy examination of liver is very helpful to identify
silent liver diseases like hepatic steatosis, cirrhosis, venous congestion and malignant tumours.
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