Estimation the Level of Metals (Lead, Cadmium, Copper and Zinc) In Multiple Sclerosis Patients in Basra\ Iraq

Authors

  • Ali Diame Nashmi 1 , Ali Faris Hassan2 , Mazin Mohamed Hammady3

DOI:

https://doi.org/10.37506/ijfmt.v14i3.10508

Keywords:

heathy metals, health; Patients; critical levels

Abstract

Multiple sclerosis (MS) is a demyelinating inflammatory disease of the central nervous system white

matter that displays a triad of pathogenic symptoms. The toxicity of heavy metals can disrupt or damage

central nervous systems. Long-term exposure of human population to heavy metals has shown neurological

impairments. The degenerative processes are similar to Alzheimer’s disease; Parkinson’s disease.This study

compared the serum level of Lead, Cadmium, Copper and Zinc in MS patients with their levels in a control

group. Methods: prospective study of cohort includes fifty Iraqi people selected from the Southern area

of Multiple Sclerosis Clinic Center divided into two groups, in which the first group contains twenty five

patients with MS and twenty five people without MS. Serum level of Lead, Cadmium, Copper and Zinc have

been measured. Results:In the present study, there was a significant increase in the concentration of (cupper

- lead –cadmium) in patients with multiple sclerosis as compared with normal people (p<0.05). There is a

significant decrease in the concentration of zinc in patients with multiple sclerosis as compared with normal

people (p<0.05).Conclusion: Lead, copper, cadmium and zinc could affect on the susceptibility of patients

to induce MS attack.

Author Biography

Ali Diame Nashmi 1 , Ali Faris Hassan2 , Mazin Mohamed Hammady3

1 Pharmacist post graduate. Department of Pharmacy/ Basra Directorate/Iraq, 2Lec. Dr. Departments of

Pharmacology and Toxicology / College of Pharmacy / University of Baghdad/Iraq, 3 Assist Prof Dr. College of

Medicine/ University of Basra/Iraq

Published

2020-07-30

How to Cite

Ali Diame Nashmi 1 , Ali Faris Hassan2 , Mazin Mohamed Hammady3. (2020). Estimation the Level of Metals (Lead, Cadmium, Copper and Zinc) In Multiple Sclerosis Patients in Basra\ Iraq. Indian Journal of Forensic Medicine & Toxicology, 14(3), 1029-1035. https://doi.org/10.37506/ijfmt.v14i3.10508