Oral Candidiasis in Chronic Kidney Disease
Keywords:Oral candidiasis ,Chronic Kidney diseases, Candida albicans
Objective : The study aims to : 1.Identification and isolation of candida spp in Patients with renal dialysis.
2.To identify the relationship between some important parameters(age , gender ,other disease) associated
with chronic kidney disease and oral candidiasis. 3.Study of antifungal susceptibility profile for C. albicans
in oral candidiasis. This study was performed in AL- Zahraa Teaching Hospital (Kidney Center) Wasit
Governorate during the period from the first of December 2018 to the end of July 2019.The samples were
collected from oral swabs ,then cultured on sabouraud dextrose agar (SDA) , examined under microscope to
show hypha and pseudohypha of Candida spp and cultured on chrom agar for identifying the Candida spp.
The molecular methods that used in this study were vitek 2 system and Polymerase chain reaction(PCR). The
results showed that from 50 oral sample from Patients with renal dialysis 24 (48%) infected with Candidiasis
20 (83.3%)was C.albicans and 4 (16.7%)other Candida Spp (C.Famata, C.Prosabilosis and C.Tropicalis) ,
while 26 (52%) non infected. There is not relationship between the age ,gender and other disease in chronic
kidney disease and the infections with oral candidiasis.
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