Correlation between Hormonal and Biochemical Changes with Kidney Function in Newly and Previously Diagnosed Women Diseased with Polycystic Ovary Syndrome

Authors

  • Zahraa Abed al-kareem 1 , Jinan Hussein Multag 2 , Ban Hoshi Khalaf 3, Amal Umran Mosa4

DOI:

https://doi.org/10.37506/ijfmt.v14i3.10583

Keywords:

Biochemical changes, kidney, women, polycystic ovary syndrome.

Abstract

The objectives of our work was to identify the effects of insulin resistance and other hormonal changes on

kidney function in newly and previously diagnosed women diseased with PCOS.

Method: This prospective study was done by collect serum samples and urine from three group (Control

60), (previously 50), (newly 50) patients. The withdrawal led samples were subsequently assay for hormonal

and biochemical changes.

Results: The data of tests were available for both groups. We found significant differences in level of

insulin, Homeostatic model assessment Insulin resistance (HOMA-IR), Homeostatic model assessment

Beta function (HOMA-B), Progesterone among newly and previous women, also the data indicated a

significant correlation between urea and testosterone in newly while direct significant correlation between

urea and progesterone. There was significant correlation between Thyroid stimulating hormone (TSH) and

creatinine in previously diagnosed PCOS, also direct correlation between uric acid and Body mass index

(BMI), Fasting blood glucose (FBS), HOMA IR and inverse correlation with Triiodothyronine (T3) in new

PCOS while in previously diagnosed PCOS there is inverse correlation between uric acid and T3. Finally,

significant correlation between FBS, insulin, HOMA B and HOMA IR in previously diagnosed patients

while correlation is seen between FBS, insulin and HOMA IR in newly patients.

Author Biography

Zahraa Abed al-kareem 1 , Jinan Hussein Multag 2 , Ban Hoshi Khalaf 3, Amal Umran Mosa4

1 M.Sc., Department of Pharmacology and Toxicology, College of Pharmacy,University of Kerbala, Kerbala, Iraq), 2

Lecturer, Dr., Karbala Hospital for Gynnecology and Obstetrics), 3 Lecturer, Dr., Department of Pharmacology

and Toxicology, College of Pharmacy, University of Kerbala, Kerbala, Iraq), 4 M.Sc., Department of Pharmacology

and Toxicology, College of Pharmacy, University of Kerbala, Kerbala, Iraq

Published

2020-07-30

How to Cite

Zahraa Abed al-kareem 1 , Jinan Hussein Multag 2 , Ban Hoshi Khalaf 3, Amal Umran Mosa4. (2020). Correlation between Hormonal and Biochemical Changes with Kidney Function in Newly and Previously Diagnosed Women Diseased with Polycystic Ovary Syndrome. Indian Journal of Forensic Medicine & Toxicology, 14(3), 1358-1366. https://doi.org/10.37506/ijfmt.v14i3.10583