Morphological Changes in Ovaries in Rats with Experimental Polycystic Ovary
Keywords:morphology, endocrine infertility, experimental and control groups, fibrosis, cyst.
Polycystic ovary syndrome is one of the important causes of infertility, metabolic syndrome. Complications
of PCOS are a serious health hazard. The relevance of the study of morphological changes in the ovaries
in rats is justified by the need to improve the treatment of PCOS. The experiment consisted in the fact that
rats from the experimental group received testosterone for 7 days and were in constant artificial daylight for
60 days. As a result of histological examination of the ovaries in this group, multiple cysts, foci of fibrosis
were found. Vaginal smears in rats from the experimental and control groups were collected and compared.
The extracted ovaries of rats of the experimental and control groups were compared, the differences in
colour according to Van Gieson X 100, haematoxylin-eosin X 40, haematoxylin-eosin X 100, B-G X 100
were analysed. Studies indicated oestrous cycle disturbance, hormonal changes in rats with experimental
polycystic. The work can serve as material for further studies aimed at identifying fast and easily accessible
methods for the diagnosis of metabolic syndrome predictors.
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