Morphological Changes in Ovaries in Rats with Experimental Polycystic Ovary

Authors

  • Chinara S. Zhylkichieva1 , Konstantin R. Nifontov2

Keywords:

morphology, endocrine infertility, experimental and control groups, fibrosis, cyst.

Abstract

Polycystic ovary syndrome is one of the important causes of infertility, metabolic syndrome. Complications

of PCOS are a serious health hazard. The relevance of the study of morphological changes in the ovaries

in rats is justified by the need to improve the treatment of PCOS. The experiment consisted in the fact that

rats from the experimental group received testosterone for 7 days and were in constant artificial daylight for

60 days. As a result of histological examination of the ovaries in this group, multiple cysts, foci of fibrosis

were found. Vaginal smears in rats from the experimental and control groups were collected and compared.

The extracted ovaries of rats of the experimental and control groups were compared, the differences in

colour according to Van Gieson X 100, haematoxylin-eosin X 40, haematoxylin-eosin X 100, B-G X 100

were analysed. Studies indicated oestrous cycle disturbance, hormonal changes in rats with experimental

polycystic. The work can serve as material for further studies aimed at identifying fast and easily accessible

methods for the diagnosis of metabolic syndrome predictors.

Author Biography

Chinara S. Zhylkichieva1 , Konstantin R. Nifontov2

1 Associate Professor at the Department of Pathology, International School of Medicine, 720054, 1F, Intergelpo

Str., Bishkek, Kyrgyz Republic, 2 Associate Professor at the Department of Internal Noncommunicable Diseases,

Pharmacology and Obstetrics named after Professor G.P. Serdtsev, Yakut State Agricultural Academy, 677007, 3,

Sergelyakhskoe Highway 3 km, Yakutsk, Russian Federation

Published

2020-07-30

How to Cite

Chinara S. Zhylkichieva1 , Konstantin R. Nifontov2. (2020). Morphological Changes in Ovaries in Rats with Experimental Polycystic Ovary. Indian Journal of Forensic Medicine & Toxicology, 14(3), 1821-1826. Retrieved from http://medicopublication.com/index.php/ijfmt/article/view/10682