Correlation Between Influenza Virus Replication and ATP6V0C of Trivalent Influenza (TIV) Vaccination in Ferret

Authors

  • Ira Humairah1,2, Reviany V. Nidom3 , Setyarina Indrasari3,4, Ema Qurnianingsih2 , Arif Nur Muhammad Ansori3,4, Irine Normalina1,3, Chairul Anwar Nidom3,6

Keywords:

ATP6V0C expression, ferret, TIV vaccination, viral replication

Abstract

Influenza virus infections are a major public health threat. Influenza viruses are associated with high

mortality and morbidity worldwide through seasonal epidemics. Vaccination programs are available, but

unpredictable antigenic changes in circulating strains require annual modification of seasonal influenza

vaccines. Influenza vaccines are given, one of which is a trivalent influenza vaccine (TIV) aimed at the

formation of antibodies that are specific to influenza viruses by B cells. In this study TIV vaccination has an

effect in the form of decreasing viral replication in ferret that have been tested with H1N1 and H3N2 viruses.

The results of this study are data about viral replication obtained from hemagglutination tests (HA test) and

ATP6V0C expression with SDS-Page.

Author Biography

Ira Humairah1,2, Reviany V. Nidom3 , Setyarina Indrasari3,4, Ema Qurnianingsih2 , Arif Nur Muhammad Ansori3,4, Irine Normalina1,3, Chairul Anwar Nidom3,6

1 Doctoral Student, Faculty of Medicine, Universitas Airlangga, Surabaya, 60286, Indonesia, 2Lecturer,

Department of Biochemistry, Faculty of Medicine, Universitas Airlangga, Surabaya, 60286, Indonesia,

3Researcher, Professor Nidom Foundation, Surabaya, 60115, Indonesia, 4Doctoral Program in Veterinary Science,

Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, 60115, Indonesia, 6Professor, Faculty of

Veterinary Medicine, Universitas Airlangga, Surabaya, 60115, Indonesia

Published

2020-07-30

How to Cite

Ira Humairah1,2, Reviany V. Nidom3 , Setyarina Indrasari3,4, Ema Qurnianingsih2 , Arif Nur Muhammad Ansori3,4, Irine Normalina1,3, Chairul Anwar Nidom3,6. (2020). Correlation Between Influenza Virus Replication and ATP6V0C of Trivalent Influenza (TIV) Vaccination in Ferret. Indian Journal of Forensic Medicine & Toxicology, 14(3), 1957-1962. Retrieved from http://medicopublication.com/index.php/ijfmt/article/view/10707