Assessment of Serum Visfatin Levels in Patients with Chronic Obstructive Pulmonary Diseases in Babylon-Iraq
Keywords:COPD , visfatin , Lipid profile, CRP .
The presented study aims to evaluate of the levels of serum Visfatin, in patients with chronic obstructive
Pulmonary diseases in Babylon-Iraq , to find the correlation of Visfatin, with lipid profile in these patients
and compared with apparently healthy as case – control study. The study included (50) patients as patients
group diagnosed with COPD (G1) and (50)as apparently control group(G2) .The age of all studied groups
ranged between (40-65)years and BMI with (18.8-24.4) Kg/m2 .Serum was used in determination of FBS,
lipid profile( Ch,TG,HDL-c,LDL-c and VLDL-c) , insulin , CRP and Visfatin , Whole blood was used for
determination of HbA1C . The results revealed significant elevation in FBG and HbA1c levels were seen
in patients groups when comparing to healthy control .The results indicates a significant elevation in TC,
TG ,LDL-c and VLDL-c in G1 comparing to G2. Also , HDL-c significant decreased in G1 comparing
to G 2 , Also ,the results showed significant increased in CRP levels in G1 , when comparing to G2, A non
significant visfatin and insulin level in G1 when compared with G2(p value = 0.486) , . A non significant
correlation was found in G1 between visfatin ,TC,TG, HDL-c and VLDL-c.
The conclusion from this study indicate that G1 which HDL-c is low in this group has the highest value
for FBS , HbA1c , TC ,TG,LDL and VLDL .Also, the study found non correlation between lipid profile
parameters in G1
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