Continuous Flow Injection Analysis,Turbidmetric and Photometric Determination of Methyldopa Using a New Long Distance Chasing Photometer (NAG-ADF-300-2)

Authors

  • Nagam S. Turkey1 , Elham N. Mezaal2

DOI:

https://doi.org/10.37506/ijfmt.v14i4.11810

Keywords:

Methyldopa, Attenuation of light, Continuous flow injection analysis, Turbidity.

Abstract

A specific, sensitive and new simple method was used for the determination of methyldopa in pure and
pharmaceutical formulations by using continuous flow injection analysis. This method is based on formation
of ion pair compound between methyldopa and potassium hexacyanoferrate in acidic medium to obtain a
yellow precipitate complex using long distance chasing photometer (NAG-ADF-300-2). The linear range
for calibration graph was 0.05-35 mmol/L for cell A and 0.05-25 mmol/L for cell B, and LOD 1.4292 µg
/200 µL for both cells with correlation coefficient (r) 0.9981 for cell A and 0.9994 for cell B, RSD% was
lower than 0.5 % for n=8 for. The results were compared with classical method UV-Spectrophotometric at
? max=280 nm and turbidmetric method by using the standard addition method via the use of t-test, at 95%
confidence level. The comparison of data explain that long distance chasing photometer (NAG-ADF-300-2)
is the choice with excellent extended detection and wide application.

Author Biography

  • Nagam S. Turkey1 , Elham N. Mezaal2

    1
    Prof. Department of Chemistry, College of Science, University of Baghdad, sBaghdad, Iraq, Department of
    chemistry, College of Education for Pure Sciences (Ibn-Al-Haitham), University of Baghdad, Baghdad, Iraq

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Published

2020-10-29

How to Cite

Continuous Flow Injection Analysis,Turbidmetric and Photometric Determination of Methyldopa Using a New Long Distance Chasing Photometer (NAG-ADF-300-2). (2020). Indian Journal of Forensic Medicine & Toxicology, 14(4), 1835-1841. https://doi.org/10.37506/ijfmt.v14i4.11810