Claudin is an Immunohistochemical Changes Associated with Experimental Infection of White Mice with 0111 – of non – 0157 Shiga Toxin Producing Escherichia Coli

Authors

  • Khalil H. ALjeboori1 , Mukhald A. Ramadhan2

DOI:

https://doi.org/10.37506/ijfmt.v14i4.11834

Keywords:

infection ; health; Escherichia coli ; Immunohistochemical

Abstract

Immunohistochemical stain for the tissue sections prepared from experimental infection of mice with 0111 –
of non 0157 of shiga toxin producing Escherichia coli .The immunohistochemical changes revealed that the
shiga toxin produced by 0111 –STEC effect on epithelial tight Junction ,The IHC stain was directed to detect
the claudin ( the structural protein of tight Junction ) revealed absence of this protein in the paracellular sites
with discohesion of the epithelial cells in the intestine and endothelial cells in the brain blood vessels which
was responsible for induction of diarrhea and nervous signs

Author Biography

  • Khalil H. ALjeboori1 , Mukhald A. Ramadhan2

    Prof . Dr. College of Dentistry , Al-Iraqia University /Iraq, 2Assit Prof. Dr. College of Medicine, University of
    Misan, Iraq

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Published

2020-10-29

How to Cite

Claudin is an Immunohistochemical Changes Associated with Experimental Infection of White Mice with 0111 – of non – 0157 Shiga Toxin Producing Escherichia Coli. (2020). Indian Journal of Forensic Medicine & Toxicology, 14(4), 1953-1960. https://doi.org/10.37506/ijfmt.v14i4.11834