Association among Vitamin D Deficiency with some Inflammatory Marker in Iraqi Patients with Autoimmune Thyroiditis

Authors

  • Noor Alhuda Kh. Ibrahim1, Zaid Nsaif Abbas2, Wasnaa J. mohammad1

Keywords:

Vitamin D; autoimmune thyroiditis; Iraqi patients

Abstract

Background: Hashimoto thyroiditis (HT) is a common chronic autoimmune disease of the thyroid gland, characterized by painless goiter and elevated thyroid antibodies. Hypovitaminosis D (vitamin D insufficiency and deficiency) is common among patients with HT.
Method: : the study include (60) subjects compared with 30 apparently healthy control group were visiting nursing home hospital in Baghdad medical city, Levels of serum thyroid-stimulating hormone (TSH), free-triiodothyronine (FT3), free thyroxine (FT4), TgAbs, and TPOAbs were determined with automated immuno chemiluminescent assay (ICMA) kits (Abbott Laboratories, IL, USA). Levels of serum 25-hydroxyvitamin D 25(OH) D) were determined using a competitive protein-binding assay (Roche Diagnostics, Mannheim, Germany). The inter-assay variation coefficient for 25(OH)D measurement was 8.5%.
Results: the level of the study parameters in autoimmune thyroiditis which show significant correlation in age ,BMI, vitamin D, anti TPO antibody,IL-17, TNF-? and thyroid function (p<0.05) (p<0.01) test but calcium shoe non significant correlation between patients and control group.
Conclusion: The present work shows a significant association between circulating 25(OH)D and HT, also IL-17.

Author Biography

Noor Alhuda Kh. Ibrahim1, Zaid Nsaif Abbas2, Wasnaa J. mohammad1

1College of Nursing University of Baghdad/ Baghdad, Iraq, 2College of biotechnology/Al-Nahrain University / Baghdad, Iraq, 3College of Nursing /University of Baghdad/ Baghdad, Iraq

Published

2020-01-16

How to Cite

Noor Alhuda Kh. Ibrahim1, Zaid Nsaif Abbas2, Wasnaa J. mohammad1. (2020). Association among Vitamin D Deficiency with some Inflammatory Marker in Iraqi Patients with Autoimmune Thyroiditis. Indian Journal of Forensic Medicine & Toxicology, 14(1), 655-660. Retrieved from http://medicopublication.com/index.php/ijfmt/article/view/125