Association among Vitamin D Deficiency with some Inflammatory Marker in Iraqi Patients with Autoimmune Thyroiditis
Keywords:Vitamin D; autoimmune thyroiditis; Iraqi patients
Background: Hashimoto thyroiditis (HT) is a common chronic autoimmune disease of the thyroid gland, characterized by painless goiter and elevated thyroid antibodies. Hypovitaminosis D (vitamin D insufficiency and deficiency) is common among patients with HT.
Method: : the study include (60) subjects compared with 30 apparently healthy control group were visiting nursing home hospital in Baghdad medical city, Levels of serum thyroid-stimulating hormone (TSH), free-triiodothyronine (FT3), free thyroxine (FT4), TgAbs, and TPOAbs were determined with automated immuno chemiluminescent assay (ICMA) kits (Abbott Laboratories, IL, USA). Levels of serum 25-hydroxyvitamin D 25(OH) D) were determined using a competitive protein-binding assay (Roche Diagnostics, Mannheim, Germany). The inter-assay variation coefficient for 25(OH)D measurement was 8.5%.
Results: the level of the study parameters in autoimmune thyroiditis which show significant correlation in age ,BMI, vitamin D, anti TPO antibody,IL-17, TNF-? and thyroid function (p<0.05) (p<0.01) test but calcium shoe non significant correlation between patients and control group.
Conclusion: The present work shows a significant association between circulating 25(OH)D and HT, also IL-17.
How to Cite
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Re use and mixing of content policy- We follow Creative Commons Licence Policy. We follow CC BY. Please refer below for all details
This license lets others distribute, remix, adapt, and build upon our work, even commercially, as long as they credit us for the original creation.
- The journal allows readers to read, download, copy, distribute, print, search, or link to the full texts of its articles and allow readers to use them for any other lawful purpose.
- The journal allows the author(s) to hold the copyright without restrictions.
- The journal allows the author(s) to retain publishing rights without restrictions