To Determine the Role of Clonidine as an Adjuvant to Intrathecal Bupivacaine in Patients Undergoing Lower Abdominal Surgery

Authors

  • Priyanka Deshmukh1 , Pratibha Deshmukh2 , Sohal Parate3 , Aruna Chandak4

DOI:

https://doi.org/10.37506/ijfmt.v14i4.12581

Keywords:

Spinal Anaesthesia, Clonidine, Lower Abdominal Surgeries, Post-op Analgesia.

Abstract

Background: Clonidine is an alpha-2 adrenergic agonist with various actions, one of which enhances the
effectiveness of local anaesthetics. For patients undergoing lower abdominal surgery, we examined the effect
of adding intrathecal clonidine to hyperbaric bupivacaine on postoperative pain relief and side effects, if any.
Aim: To assess the efficacy of intrathecal clonidine along with hyperbaric Bupivacaine in patients undergoing
lower abdominal surgeries.
Method: It was a retrospective study carried out under spinal anaesthesia on 80 patients undergoing lower
abdominal surgery. The research population was assigned randomly to two groups; group B- received 15 mg
bupivacaine+ 0.4mi Normal Saline and group C received 15 mg bupivacaine + 60mcg clonidine.
Results: Addition of 60mcgs of intrathecal clonidine to 0.5% hyperbaric bupivacaine significantly prolonged
the duration of motor & sensory blockade along with the duration of effective postoperative analgesia. The
demand for rescue analgesic was earlier in group B as compared to group C. Both groups were matched for
the side-effects like hypotension, bradycardia, nausea, vomiting, and shivering

Author Biography

  • Priyanka Deshmukh1 , Pratibha Deshmukh2 , Sohal Parate3 , Aruna Chandak4

    1Assistant Professor Dept. of Anaesthesiology Datta Meghe Medical College, Shalinitai Meghe Hospital and
    Research Centre, Wanadongri, Hingana, Nagpur-441110, 2
    Professor and HOD Dept. of Anaesthesiology Datta
    Meghe Medical College, Shalinitai Meghe Hospital and Research Centre, Wanadongri, Hingana, Nagpur-441110,
    3Senior resident Dept. of Anaesthesiology Datta Meghe Medical College, Shalinitai Meghe Hospital and Research
    Centre, Wanadongri, Hingana, Nagpur-441110, 4Professor Dept. of Anaesthesiology, Jawaharlal Nehru Medical
    College, Datta Meghe Institute of Medical Sciences, Sawangi, Wardha-442001

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Published

2020-10-29

How to Cite

To Determine the Role of Clonidine as an Adjuvant to Intrathecal Bupivacaine in Patients Undergoing Lower Abdominal Surgery. (2020). Indian Journal of Forensic Medicine & Toxicology, 14(4), 6266-6272. https://doi.org/10.37506/ijfmt.v14i4.12581