Role of Prolactin and ?-hCG in Female Infertility

Authors

  • Mahendra Dhabe1 , Ranjit S. Ambad2 , Archana Dhok3

DOI:

https://doi.org/10.37506/ijfmt.v14i4.12702

Keywords:

Prolactin, female infertility, hCG.

Abstract

The World Health Organization (WHO) describes infertility as a disability for couples in childbirth to
attain pregnancy within 12 months of daily sexual intercourse. Infertility affects 13–20 per cent of couples
worldwide, regardless of race or ethnicity. Human chorionic gonadotropin (hCG), also known as the
“pregnancy hormone,” plays a significant role in human reproduction. The present study was conducted
in the departments of biochemistry and dept. of obstetrics and gynaecology. The study was conducted on
two groups of 40 infertile Females and 40 healthy controls. Blood sample was collected for the estimation
of prolactin and hCG was assessed by dry chemistry analyzer. Serum prolactin levels in infertile females is
33.96±11.46 and hCG levels was86.38±12.45 which was higher in infertile female as compare to healthy
control with a p value of<0.05. Present study concludes that hyperprolactinemia is a major contributing
hormonal factor in infertility among infertile women and, as such, prolactin and hCG should be measured
in infertile women.

Author Biography

  • Mahendra Dhabe1 , Ranjit S. Ambad2 , Archana Dhok3

    1
    Associate Professor, Dept of Biochemistry, Swami Ramanand Teerth Rural Medical College, Ambajogai,
    2
    Associate Professor Dept. of Biochemistry Datta Meghe Medical College, Shalinitai Meghe Hospital & Research
    Centre, Hingana, Nagpur, Maharashtra-441110, 3
    Professor & Head Dept. of Biochemistry, Jawaharlal Nehru
    Medical College, DMIMSU, Sawangi, Wardha.

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Published

2020-10-29

How to Cite

Role of Prolactin and ?-hCG in Female Infertility. (2020). Indian Journal of Forensic Medicine & Toxicology, 14(4), 6863-6867. https://doi.org/10.37506/ijfmt.v14i4.12702