Isoniazid Mono Resistance: Changing Trends in Drug Resistant Pulmonary Tuberculosis. – A Case Series of 3 Patients

Authors

  • Arti D. Shah1 , Anchal Jain2 , Apoorva3 , Kusum V. Shah4 , Yash Rana5 , Saket kumar6

DOI:

https://doi.org/10.37506/ijfmt.v15i1.13368

Keywords:

INH mono resistance, LPA, MDR TB.

Abstract

Drug resistant tuberculosis is a major public health concern in many countries including India, Isoniazid
resistance (INH) accounts for 7.2 % of new cases globally.1
In our case series 3 patients had INH mono
resistance out of which 2 patients had no previous history anti tuberculosis therapy (ATT). All 3 patients
received 6 months of standard regimen under National Tuberculosis Elimination Programme (NTEP).
All patients showed clinical improvement. INH mono resistance diagnosis is often delayed due to lack of
infrastructure of 1st line probe assay (LPA) at various centres. INH mono resistance if diagnosed early can
also help in prevention of Multi drug resistant tuberculosis (MDR TB)

Author Biography

Arti D. Shah1 , Anchal Jain2 , Apoorva3 , Kusum V. Shah4 , Yash Rana5 , Saket kumar6

1
Professor and Head of Department, 23rd year Post Graduate Resident, 33rd year Post Graduate Resident,
4Professor, 5Assistant Professor ,63rd year Post Graduate Resident, Department of Respiratory Medicine,
Smt. S.B.K.S. Medical Institute & Research Centre, Sumandeep Vidyapeeth Deemed to be University, Piparia
(Vadodara)- 391760 (India)

Published

2020-12-31

How to Cite

Arti D. Shah1 , Anchal Jain2 , Apoorva3 , Kusum V. Shah4 , Yash Rana5 , Saket kumar6. (2020). Isoniazid Mono Resistance: Changing Trends in Drug Resistant Pulmonary Tuberculosis. – A Case Series of 3 Patients. Indian Journal of Forensic Medicine & Toxicology, 15(1), 17-19. https://doi.org/10.37506/ijfmt.v15i1.13368