Isoniazid Mono Resistance: Changing Trends in Drug Resistant Pulmonary Tuberculosis. – A Case Series of 3 Patients
DOI:
https://doi.org/10.37506/ijfmt.v15i1.13368Keywords:
INH mono resistance, LPA, MDR TB.Abstract
Drug resistant tuberculosis is a major public health concern in many countries including India, Isoniazid
resistance (INH) accounts for 7.2 % of new cases globally.1
In our case series 3 patients had INH mono
resistance out of which 2 patients had no previous history anti tuberculosis therapy (ATT). All 3 patients
received 6 months of standard regimen under National Tuberculosis Elimination Programme (NTEP).
All patients showed clinical improvement. INH mono resistance diagnosis is often delayed due to lack of
infrastructure of 1st line probe assay (LPA) at various centres. INH mono resistance if diagnosed early can
also help in prevention of Multi drug resistant tuberculosis (MDR TB)
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