Causative Microorganisms and Antibiotics Susceptibility in Neonatal Sepsis at Neonatal Intensive Care Unit: A Longitudinal Study from Diyala Governorate in Iraq

Authors

  • Issam Tariq Abdul Wahaab1 , Sura Qais Mahmood Almaroof 2, Zaid Taha Yaseen3

DOI:

https://doi.org/10.37506/ijfmt.v15i1.13382

Keywords:

Anti-Bacterial Agents; Antibiotics Resistance; Causative Microorganisms; Intensive Care Units; Iraq; Middle East; Neonatal Sepsis; Neonatology.

Abstract

Background: Neonatal sepsis is classified into two types, early-onset and late-onset sepsis, depending on
the time of appearance of the clinical features of neonatal sepsis.
Objective: We aim to detect the most common causative organisms of neonatal sepsis and to evaluate the
corresponding antibiotics susceptibility in the Diyala governorate.
Patients and Methods: We prospectively collected a convenient sample of 106 sepsis-proven neonates
from the neonatal intensive care unit at Al-Batool teaching hospital. We assessed all cases based on clinical
features, laboratory investigations, and demographics.
Results: Late-onset neonatal sepsis was predominant (77.4%) among neonates, and it was significantly
associated with neonatal prematurity and the mode of delivery at p-values of 0.03 and 0.045 respectively.
Premature neonates and those who were the product of cesarean section were more prone to develop
late-onset neonatal sepsis with a relative risk of 2.8 and 2.54 respectively. The most common causative
microorganism of early-onset neonatal sepsis was found to be Escherichia coli in 45.8% of cases while
those causing late-onset neonatal sepsis were mainly due to Gram-negative bacilli represented by Klebsiella
pneumonia (46.3%) and Acinetobacter baumannii (24.4%). Multi-drug resistance was evident for most of
the causative microorganisms.
Conclusion: To recapitulate, late-onset sepsis appeared was more common among Iraqi neonates, and it was
significantly associated with the neonate prematurity and C-section mode of delivery.

Author Biography

Issam Tariq Abdul Wahaab1 , Sura Qais Mahmood Almaroof 2, Zaid Taha Yaseen3

1
Lecturer in Department of Anatomy/ College of Medicine, University of Baghdad, Iraq, 2Senior House office in
Department of Pediatric/ Neonatology Unit, Diyala Health Directorate, Iraq, 3Senior House Office in Department
of Pediatric/ Neonatology Unit, Diyala Health Directorate, Iraq

Published

2020-12-31

How to Cite

Issam Tariq Abdul Wahaab1 , Sura Qais Mahmood Almaroof 2, Zaid Taha Yaseen3. (2020). Causative Microorganisms and Antibiotics Susceptibility in Neonatal Sepsis at Neonatal Intensive Care Unit: A Longitudinal Study from Diyala Governorate in Iraq. Indian Journal of Forensic Medicine & Toxicology, 15(1), 101-110. https://doi.org/10.37506/ijfmt.v15i1.13382