Effect of Serotonin Concentration and Some Variables in the Sera 6 hours before and after Dialysis on Chronic Kidney Patients with Different Ages in Iraqi Population
Keywords:serotonin , Before and after dialysis, hemoglobin, uric acid, creatinine
This study is concerned with chronic kidney disease and control group . The determine patients from (alseder
hospital ) in Najaf city during the period between January 2019 to July 2019. The CKD patient and control
group consisted of sixty with age mean of (80 ±20) years. The blood samples were drawn from all patients 6
hours before and after dialysis to measurement serotonin , blood Urea, Creatinine , uric acid and hemoglobin
and control group. Also the patients classified into two groups according to age . This variables measured by
using assay (ELISA) technique and colorimetric methods. The higher mean value of serotonin was shown
in CKD patients before dialysis ( 0.0257± 0.00224 ng /ml) compared with patients after dialysis ( 0.1894 ±
0.05189 ng/ml) compared with control group( 0.0059 ± 0.00139 ng/ml). Also the higher value of blood Urea
and Creatinine reversibly in CKD patients before dialysis was (126.25± 4.869 mg/dL), (10.041± 0.3019
mg/dL) compared in blood Urea and Creatinine in CKD patients after dialysis was (48.183± 2.262 mg/dL),
(3.28± 0.201 mg/dL) and control group was (28.105 ± 1.896 mg/dL), (1. 095 ± 0.0961 mg/dL).
Also the higher value of uric acid and hemoglobin reversibly in CKD patients before dialysis was (8.0623±
0.1478 mg/dL), (13.800 ± 0.16519 g/dL) compared in uric acid and hemoglobin in CKD patients after
dialysis was (5.5361± 0.16055 mg/dL), (12.383 ± 0.15872 g/dL) and control group was (2.6789 ± 0.2977 mg/
dL), (13.742 ± 0.18954 g/dL) , all above results there was a significant difference and correlation (p?0.05).
Aim of study: Study the effect of serotonin, blood Urea, Creatinine , uric acid and hemoglobin 6 hours
before and after dialysis on CKD patients and compared with control group .Study the effect of variables
on CKD patients with different age and study the relation between CKD patients after and before dialysis.
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