The Significance of CD4 to the Number of Grown Candida Colonies in Oral Candidiasis Patients with HIV / AIDS
Keywords:CD4 count, HIV/AIDS, candida species, oral candidiasis
Introduction: Oral candidiasis is a common symptom in HIV/AIDS patients and in some cases have low CD4
levels. Objectives: Analyzing the correlation of CD4 counts with Candida colonization in oral candidiasis
patients with HIV/AIDS. Methods: The research procedure consisted of identifying the type and number
of Candida species grown in the participant’s oral cavity, and calculating the CD4 count. The statistical
tests used Chi Square, Fisher exact, Spearman correlation test, or Anova test (95% CI; p <0.05). Results:
Candida colonization found in group I was 1 – 10 (71.05%), group II was 11-100 (60.53%), and group
III was >100 (50.00%; p <0.001). The patient’s lesion area in group I was 3-4 (47.37%), group II was
3-4 (65.79%), and group III was 1-2 (94.74%; p <0.001). Most patients had acute pseudomembranous type,
consisting of 81.58% (group I), 92.10% (group II), and 97.37% (group III; p <0.001). Conclusion: This
study found a significant correlation between CD4 counts and Candida colonization in oral candidiasis
patients with HIV/AIDS. The lower the CD4 counts, the higher the number of Candida colonization in
the oral cavity
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