Impact of Bone Marrow Mesenchymal Stem Cells on Different Body Organs of Albino Rats Exposed To Cadmium Chloride Toxicity: A Systematic Review

Authors

  • Elham H. Ahmed 1, Mohammed E. Grawish2 , Mohamed Abdulrahman3 , Menatalla M. Elhindawy4 , Mohamad E. Helal2

DOI:

https://doi.org/10.37506/ijfmt.v15i1.13552

Keywords:

Cadmium chloride; bone marrow stem cells; rats; systematic review.

Abstract

Background and Objective: Cadmium chloride (Cd cl2) is a highly toxic heavy metal that causes severe
degenerative effects to different body organs. Bone marrow mesenchymal stem cells (BMMSCs) may have
a protective effect upon CdCl2 induced structural and functional changes in the rat’s organs. This systematic
review aimed to test the regenerative effects of bone marrow?derived mesenchymal stem cells on different
body organs of albino rats exposed to cadmium chloride toxicity.
Methods: Experimental animal studies were identified by the following electronic databases: PubMed,
Scopus, Ovid Medline, KoreaMed, Google Scholar, Latin American and Caribbean Health Sciences
Literature (LILACS) and Central Cochrane Library. The literature search was done from January 2010 to
2020.
Conclusion: From the selected articles, using stem cell therapy enhances the regeneration process in CdCl2
toxicity of different body organs.

Author Biography

Elham H. Ahmed 1, Mohammed E. Grawish2 , Mohamed Abdulrahman3 , Menatalla M. Elhindawy4 , Mohamad E. Helal2

1Assistant Lecturer, Faculty of Dentistry, Mansoura University, Egypt, 2Professor of Oral Biology, Faculty of
Dentistry, Mansoura University, Egypt 3Assistant Professor of Oral Biology, Faculty of Dentistry, Mansoura
University, Egypt, 4Lecturer of Oral Biology, Faculty of Dentistry, Mansoura University, Egypt

Published

2020-12-31

How to Cite

Elham H. Ahmed 1, Mohammed E. Grawish2 , Mohamed Abdulrahman3 , Menatalla M. Elhindawy4 , Mohamad E. Helal2. (2020). Impact of Bone Marrow Mesenchymal Stem Cells on Different Body Organs of Albino Rats Exposed To Cadmium Chloride Toxicity: A Systematic Review. Indian Journal of Forensic Medicine & Toxicology, 15(1), 1038-1044. https://doi.org/10.37506/ijfmt.v15i1.13552