Effect of Hemodialysis on Some Biochemical Parameters in Diabetic Nephropathy Patients

Authors

  • Salahaldin M. Fahad1 , Rashied M. Rashied 2, Waleed N. Jaffal3

DOI:

https://doi.org/10.37506/ijfmt.v15i1.13624

Keywords:

Chronic kidney disease (CKD), Diabetes mellitus (DM), Hemodialysis (HD), Sodium ion, Urea

Abstract

Diabetes mellitus is a worldwide epidemic and is associated with long-term damage and causes dysfunction
of several organs like kidney leading to diabetic nephropathy. This study was designed to evaluate some
biochemical aspects.This study was conducted on 95 patients which included (35) HD patients with diabetes
and (35) HD patients without diabetes and (25) Type 2 diabetes mellitus patients, who attended at Ramadi
General Hospital. For the purpose of comparison, (25) samples as control. Several tests were performed such
as FSB, urea, creatinine, glomerular filtration rate (GFR), albumin, sodium ion, calcium ion, Phosphorus
ion, potassium ion and magnesium ion were calculated. This study showed the level of urea and creatinine
were a significant increase in HD patients with diabetes(128.29±22.59 and 7.1±1.76) mg/dl respectively,
and HD patients without diabetes were (125.74±23.28 and 6.80±2.71) mg/dl respectively. The levels of Na+
and Ca++ were decrease in HD patients with diabetes (137.6±4.8 mmol/L and 6.72±1.76mg/dl) respectively.
The levels of P, K+ and Mg++ were a significant increase in HD patients without diabetes(6.26±0.84 mg/dl,
5.52±0.61 mmol/L and 2.2±0.13mg/dl) respectively. The urea, creatinine and GFR are simple and useful
biomarkers which can serve as predictor tests for assessing kidney functions in diabetic patients.

Author Biography

Salahaldin M. Fahad1 , Rashied M. Rashied 2, Waleed N. Jaffal3

1PH.D. student, department of Biology, College of Sciences, University Of Anbar. Iraq. 2 Assistant professor
(Animal physiology), department of Biotechnology, College of Sciences, University Of Anbar. Iraq. 3Assistant
Professor(Consultant urologist), department of Surgery, College of Medicine, University Of Anbar. Iraq

Published

2020-12-31

How to Cite

Salahaldin M. Fahad1 , Rashied M. Rashied 2, Waleed N. Jaffal3. (2020). Effect of Hemodialysis on Some Biochemical Parameters in Diabetic Nephropathy Patients. Indian Journal of Forensic Medicine & Toxicology, 15(1), 1499-1504. https://doi.org/10.37506/ijfmt.v15i1.13624

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