The Accuracy of Intrinsic Compression Ultrasound Elastography (E-Thyroid) in Differentiating Benign From Malignant Thyroid Nodule
Keywords:Ultrasound Elastography, (E-Thyroid), Benign Thyroid Nodule, Malignant Thyroid Nodule, Elasticity, ECI value, Cut-off
Background: Ultrasound elastography (USE) is an ultrasound-based technique that addresses the biomedical
properties of the nodules. Based on the stiffness of the tissue this technique differentiates between the benign
nodules from the malignant ones where the hard and soft tissue is determined by the high or the low elasticity
values respectively. The present study aimed to evaluate the efficacy of the E-thyroid in the differentiation
of malignant and benign thyroid nodules and also a cut off ECI value using fine-needle aspiration as the
diagnostic standard of reference
Methods: The current prospective study was done on 80 patients in the radiology department in Al Yarmouk
teaching hospital in Baghdad city from April 2018 to April 2019. All the patients referred from the outpatient
clinic. All the patients were examined sonographically starting with B mode ultrasound then elastoscan
examination was done.
Result: The study result showed that among the 80 patients 65 had a benign nodule and only 15 were
diagnosed with a malignant thyroid nodule. The ECI value and the histopathological result showed a
significant agreement in the result and a cut off ECI value of 4 were shown to be effective to diagnose the
presence of malignant thyroid nodule.
Conclusion: Overall, the present study showed that USE can be effectively used to differentiate between the
malignant and benign thyroid nodules and being a safe method this can be used widely. However, the result
of this study needs further validation with a larger study population.
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