Cytotoxic activity of Green Zinc Selenide Nanoparticles Against Hep-G2 Cell Lines

Authors

  • Sabah N. Mazhir1 , Kadhim A. Aadim2 , Mohammad M. F. Al-Halbosiy3 ,Nisreen Kh.Abdalameer4

DOI:

https://doi.org/10.37506/ijfmt.v15i1.13713

Keywords:

Cancer cell, Cytotoxicity,ZnSe green NPs, HepG2,Plasma jet.

Abstract

In the current study a new technique between the plasma physics, nanoparticle and Biotechnology,structured
(ZnSe) prepared by cold plasma technique using atmospheric pressure plasmajet system, Znse NPs were
prepared from selenium nitrate and zinc metal sheets to reduce selenium toxicity. The structural and optical
properties were characterized by X-ray diffraction (XRD) and absorbance measurements of ZnSe green
NPs. The liver cancer cell line (hepG2) was exposed to the ZnSe nanoparticles, and The percentage of
cytotoxicity was suppressed after 24, and48 from exposure, induced cytotoxicity is found to be 70.3% in
hepG2 after exposed 48h ZnSe green nanoparticle, and the maximum cytotoxicity of the normal cell line
(REF) was also examined 42.62% when exposure ZnSe nanoparticles and 16.6% when exposure ZnSe green
nanoparticles.

Author Biography

Sabah N. Mazhir1 , Kadhim A. Aadim2 , Mohammad M. F. Al-Halbosiy3 ,Nisreen Kh.Abdalameer4

1Prof,College of Science for women,a University of Baghdad,Baghdad, Iraq, 2Prof,College of Science, University
of Baghdad,Baghdad, Iraq, 3
Prof, Biotechnology Research Center/ Al-Nahrain University/Iraq, 4 Lecturer, College
of Science for Women,a University of Baghdad, Baghdad,Iraq

Published

2020-12-31

How to Cite

Sabah N. Mazhir1 , Kadhim A. Aadim2 , Mohammad M. F. Al-Halbosiy3 ,Nisreen Kh.Abdalameer4. (2020). Cytotoxic activity of Green Zinc Selenide Nanoparticles Against Hep-G2 Cell Lines . Indian Journal of Forensic Medicine & Toxicology, 15(1), 2072-2078. https://doi.org/10.37506/ijfmt.v15i1.13713