Synthesis, Characterization of New Tris Hydrazones based on Cyanuric Acid and Studies the Biological Activity as Antibacterial and Antifunga

Authors

  • Thaer Saleh Ghali

Keywords:

Cyanuric acid , Hydrazones , antibacterial, 1,3,5-Triazinane-2,4,6-trione, antifungal

Abstract

In this study synthesis of new Tris Hydrazones derived from Cyanuric acid , these compounds synthesized by reaction of Cyanuric acid with Chloro ethyl acetate to product [I], then converted it to acid Hydrazide [II] by reacted with Hydrazine hydrate(80%) in absolute ethanol as a solvent. Compound [II] refluxed with different aromatic aldehyde in present of Glacial acetic acid (GAA) as a catalyst to formation new Tris Hydrazones [III]a-f. All new compounds were synthesized characterization by FT-IR and 1H-13CNMR spectroscopy. The biological activity of new Tris Hydrazones studies against to positive and negative Gram bacteria also test it against to Candida albicans as a sample of Fungi.

Author Biography

Thaer Saleh Ghali

Directorate of Education Dhi Qar, Ministry of Education, Iraq

Published

2020-01-16

How to Cite

Thaer Saleh Ghali. (2020). Synthesis, Characterization of New Tris Hydrazones based on Cyanuric Acid and Studies the Biological Activity as Antibacterial and Antifunga. Indian Journal of Forensic Medicine & Toxicology, 14(1), 753-758. Retrieved from http://medicopublication.com/index.php/ijfmt/article/view/142