Thyroid Nodules of Iraqi Patients with Acromegaly
Keywords:thyroid nodule, acromegaly, goiter, multinodular goiter, ultrasonography
Acromegaly is a chronic endocrine disorder caused by excessive secretion of growth hormone. The incidence of malignancy like colorectal carcinoma is well documented to increase in patients with acromegaly. While the real incidence of thyroid neoplasm in these patients are not well known.
Aims: Find out the rate of structural thyroid disorders in a sample of Iraqi patients with acromegaly; Identify the rate of thyroid malignant transformation in patients with acromegaly.
Settings and Design: A case control study
Methods and Material: seventy patients with acromegaly were enrolled compared with 70 controls from 2 endocrinology centers from Jan. -Dec. 2017. Their mean age 46+/-11years ;41(58.5%) males. Thyroid ultrasound was conducted for all participants while fine needle aspirate conducted for those with nodule diameter ?1cm.
Results: . Goiter was founded more in patients with acromegaly versus control group (81.4% vs 18.5% respectively ;P<0.0001) .The overall nodular thyroid disease were found in (61.4%) acromegalic patients(of those : (11.4%) had single thyroid nodule and (50%) had multiple thyroid nodules. The ultrasonic feature of thyroid nodule were suspicious in (13.9%) of acromegaly group and none in control; P<0.0001). The fine needle aspirate results were suspicious in(9.3%) acromegaly group versus none in control group, P<0.05). One patient (2.3%) with acromegaly had papillary thyroid carcinoma and none in control; P=0.31).
Conclusions: Nodular thyroid disease were more prevalent in Iraqi patients with acromegaly but the risk of malignancy is not significantly different from normal population.
How to Cite
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Re use and mixing of content policy- We follow Creative Commons Licence Policy. We follow CC BY. Please refer below for all details
This license lets others distribute, remix, adapt, and build upon our work, even commercially, as long as they credit us for the original creation.
- The journal allows readers to read, download, copy, distribute, print, search, or link to the full texts of its articles and allow readers to use them for any other lawful purpose.
- The journal allows the author(s) to hold the copyright without restrictions.
- The journal allows the author(s) to retain publishing rights without restrictions