Indirect Method for Determination of Paracetamol in Pure and Pharmaceutical Drugs using CFIA with Homemade Ayah 3SBGRX3-3D Solar Cell Microphotometer Analyzer

Authors

  • Nagam S. Turkey Al-Awadie1, Marwah A. Kadhim Al-banaa2

Keywords:

spectrophotometer , flow injection analysis , paracetamol

Abstract

A method is described for the determination of paracetamol(based on the formation of a orange-reddish color species by reduction of Fe(III) to Fe(II) by paracetamol and then reacted with 1,10-phenanthroline) in the range 0.001-0.09mMol.L-1 (r =0.9801, r2 = 0.9606 , and R2% = 96.06) with a detection limit (LOD) 21.77ng/160?L(3SB)(S/N=3) and with RSD% for 0.01 and 0.07mMol.L-1 less than 1 % (n=6). The method was applied successfully for determination of paracetamol in pharmaceuticals formulation. Analysis of drugs used the standard additions method via the individual t-test. The results showed a significant., difference between the quoted..value of each company. with calculated t-test at 95% confidence(?=0.05) from new method.

Author Biography

Nagam S. Turkey Al-Awadie1, Marwah A. Kadhim Al-banaa2

1Department of Chemistry, College of Science, University of Baghdad, Baghdad, Iraq,
2Department of Optical Techniques, Dijlah University College, Baghdad, Iraq.

Published

2020-01-16

How to Cite

Nagam S. Turkey Al-Awadie1, Marwah A. Kadhim Al-banaa2. (2020). Indirect Method for Determination of Paracetamol in Pure and Pharmaceutical Drugs using CFIA with Homemade Ayah 3SBGRX3-3D Solar Cell Microphotometer Analyzer. Indian Journal of Forensic Medicine & Toxicology, 14(1), 851-857. Retrieved from http://medicopublication.com/index.php/ijfmt/article/view/159