Device-associated Infections (DAIs) in ICU: Using new CDC/ NHSN definitions

Authors

  • Mostafa Mohammadi1, Arash Seifi2, Maryam Mokhtaryan3, Azam Ghahan4, Sara Ghaderkhani3, Esmaeil Mohammadnejad5, Reza Ghanei Gheshlagh6

DOI:

https://doi.org/10.37506/ijfmt.v14i2.3095

Keywords:

Device associated infection; antimicrobial resistance; intensive care unit

Abstract

Surveillance of device-associated infections (DAIs) in intensive-care units (ICUs) is essential for a suitable healthcare strategy-planning. This study was conducted to determine the DAIs rate, microbial epidemiology, and antimicrobial resistance pattern (AMR) in ICU. Three major DAIs, ventilator associated pneumonia (VAP), catheter-associated urinary tract infection (CAUTI), and central line-associated bloodstream infection (CLABSI) were assessed prospectively during 6 months (2018 March 21 to September 22) in an 18-bed ICU of a tertiary teaching hospital in Tehran according to new CDC/NHSN definitions for surveillance of DAIs. The incidence of VAP, CAUTI, and CLABSI were 38.2, 8.9, and 13.5 per 1000 device-days respectively. The most organisms were Acinetobacter baumannii (34.9%), Klebsiella pneumonia (19%), E.coli (10.7%), Candida (10.7%), Enterococcus Spp. (8.7%), Pseudomonas aeruginosa (8.7%), and Staphylococcus aureus (2.9%). Klebsiella pneumoniae carbapenemase (KPC)-producing was 47.4%. Acinetobacter resistance to Ampicillin-sulbactam and carbapenems was 80.6% and more than 90% respectively. Methicillin resistant Staphylococcus aureus (MRSA) was 66.6% and Vancomycin-resistant Enterococcus (VRE) was 88.9%. This study showed high incidence of DAIs and resistant organisms in the ICU. Preventive measures are essential to decrease the rates.

Author Biography

Mostafa Mohammadi1, Arash Seifi2, Maryam Mokhtaryan3, Azam Ghahan4, Sara Ghaderkhani3, Esmaeil Mohammadnejad5, Reza Ghanei Gheshlagh6

1Associate Professor, Department of Anesthesiology and Critical Care, School of Medicine, Tehran University of Medical Science, Tehran, Iran, 2Assistant Professor , Department of Infectious Diseases, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran, 3Department of Infectious Diseases, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran, 4Department of Nursing, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran, 5Assistant Professor of Nursing, Department of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran, 6Assistant Professor, Social Determinants of Health Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran

Published

2020-04-29

How to Cite

Mostafa Mohammadi1, Arash Seifi2, Maryam Mokhtaryan3, Azam Ghahan4, Sara Ghaderkhani3, Esmaeil Mohammadnejad5, Reza Ghanei Gheshlagh6. (2020). Device-associated Infections (DAIs) in ICU: Using new CDC/ NHSN definitions. Indian Journal of Forensic Medicine & Toxicology, 14(2), 1335-1340. https://doi.org/10.37506/ijfmt.v14i2.3095