Anti malignant (HepG2, MOLT-3) Activity of One, Two, Three- Triazoles New Prepared Bearing Hetero Compounds in Baghdad

Authors

  • Ahmed Sa’adi Hassan

DOI:

https://doi.org/10.37506/ijfmt.v14i2.3110

Keywords:

1,2,3-Triazoles • Heterocyclic • Anti malignant• (HepG2, MOLT-3)

Abstract

In the current work, chemistry a group of related chemicals that are similar in structure or properties of new heterocyclic compounds were prepared from paraP.nitrobenzoic, acid. This work includes four parts: the first part Preparation of 5-(4-nitro phenyl)-1,33,4-thiaadiazol-2-amine by the reaction of p.pnitrobenzoic acid with thioseemicarbazide,the second part prepared 2-chloro-N-(5-(4-Nnitrophenyl)-1,3,4-thiadiazol2-yl) Aacetamide by reaction Chloroacetyl chloride with compound and part three contain reaction compound(2) with urea/thiourea to get compounds cyclization by using urea (thiourea) finally step reaction these compounds with different aldehydes and ketones in glacial acetic acid (6-10) , as shown in Scheme 1 The aim of present work is synthesis new derivatives of 1,2,3-Triazole having heterocyclic compounds on ring from the reaction of azine with a different reagent to give (1,2,3- Triazole) rings.The1,2,3-Triaazoles It has been derivatives A long time ago and has been Scout mainly for their potenitial in anti-tTumor chemotherapy the prepared of 11,2,3-Triazole financial products have good AAnti malignant (HepG2, MOLT-3) Activity. Many groupss have ccarried out focused research in this particularr

Author Biography

Ahmed Sa’adi Hassan

1Medical Lab Technique, College of Health and Medical Technical, Middle Technical University, Baghdad, Iraq

Published

2020-04-29

How to Cite

Ahmed Sa’adi Hassan. (2020). Anti malignant (HepG2, MOLT-3) Activity of One, Two, Three- Triazoles New Prepared Bearing Hetero Compounds in Baghdad . Indian Journal of Forensic Medicine & Toxicology, 14(2), 1411-1418. https://doi.org/10.37506/ijfmt.v14i2.3110