Immunomodulation of IraqiLyciumbarbarium Carotene in vitro
Keywords:Lyciumbarbarumactive, lymphocytes, L.barbarumconsidered, proliferation, caroteneas.
The contents of Lyciumbarbarumactive constituents as wild Iraqi plant was extracted then estimated qualitatively and quantitatively by HPLC method. Effect of the extracted carotene was employed in the current study on the normal human blood lymphocytes to estimate the extract effect on IL-6 and IL-8 levels as immune modulating agent.L.barbarumconsidered as a good source for caroteneas it’s containedwas 0.287mg/g dried fruits.The current study results about the effect of extracted carotene on normal human lymphocytes and interleukins 6 and 8 levels showed that the compound can enhance cell-mediated immune responsesthrough enhance lymphocytes proliferation with increasing in IL-8 and decrease IL-6 level
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