Effectiveness of Additional Intranasal Phototherapy through Decrease Score of Nose Symptom and Eosinophil Mucosa on Persistent Allergic Rhinitis

Authors

  • Hamna Fitriah1, Roestiniadi Djoko Soemantri1

DOI:

https://doi.org/10.37506/ijfmt.v14i2.3366

Keywords:

Allergic rhinitis, Eosinophil, Phototherapy intranasal, Loratadine

Abstract

Background: Allergic rhinitis (AR) is a common atopic disease but the available treatment has limited used and success rate. It has been suggested that intranasal phototherapy represents an alternative choice in the treatment of AR. Objective: This study aimed to analyze the effect of additional intranasal phototherapy to loratadine therapy compared with single loratadine therapy in order to decrease total nasal symptoms score (TNSS) and nasal mucosa eosinophil count in persistent AR patients. Method: Fifty-four persistent AR patients were divided into two treatment groups: group A and B treated with 10 mg loratadine once a day with additional intranasal phototherapy at 660 nm. 4.4 minutes 3 times a day for group B. Evaluation was based on TNSS and nasal mucosa eosinophil countpre and post 14 days of treatment. Result: The study conducted from July to August 2014 demonstrated significant average of TNSS decrease on group B compared to group A (p = 0.002). Also significant average of eosinophil mucosa nasal count decrease on group B compared to group A (p = 0.049). Both group A and B showed the smallest score of TNSS pre-therapy was 4 vs 6, however the highest score was 6 vs 12. Group A and B showed the smallest score of TNSS post-therapy was 0 vs 0, however the highest score was 8 vs 7. Conclusion: Additional intranasal phototherapy to loratadine therapy showed more effective compared with single loratadine therapy in order to decrease TNSS and nasal mucosa eosinophil count in persistent AR patients

Author Biography

Hamna Fitriah1, Roestiniadi Djoko Soemantri1

1Departement of Otolaryngology, Faculty of Medicine, Universitas Airlangga-Dr. Soetomo Teaching Hospital, Surabaya 60285, Indonesia

Published

2020-04-29

How to Cite

Hamna Fitriah1, Roestiniadi Djoko Soemantri1. (2020). Effectiveness of Additional Intranasal Phototherapy through Decrease Score of Nose Symptom and Eosinophil Mucosa on Persistent Allergic Rhinitis. Indian Journal of Forensic Medicine & Toxicology, 14(2), 2277-2282. https://doi.org/10.37506/ijfmt.v14i2.3366