Evaluation Inhibin B, FSH, and LH in Male with Thalassemia

Authors

  • Fatimah Kadhim Ibrahim AL- Mahdawi1, Zaid Nabeel Elia2, Hayder Abdulhafedh Kurji3

DOI:

https://doi.org/10.37506/ijfmt.v14i2.3401

Keywords:

Inhibin B, FSH, LHand thalassemia

Abstract

Background : - Hypogonadism is the most frequently reported endocrine problem, affecting 70–80% of patients with thalassemia.Aim of study: -The current study is aimed to found correlation among inhibinB,FSH, LH and testosteronein male with thalassemia. Material and Subject: The study carried out 40 healthyvolunteermale, age range between (18-30) years,and enrolled 40 patients with thalassemia major age range between 18-30 years. The concentrations serum inhibin-B was estimated by two-side enzymelinked immunosorbent assays (ELISA), While FSH, and LH estimated by using Cobas e analyzers.Results: LH reduce significantly in thalassemia patients when compared with healthy individuals, while FSH and testosterone decrease significantly in thalassemia patients when compared with healthy. Inhibin B was reduced significantly in thalassemia patients when compared with healthy individuals.Conclusion:Infertility common in thalassemia patients, that correlation with decrease inhibin B.

Author Biography

Fatimah Kadhim Ibrahim AL- Mahdawi1, Zaid Nabeel Elia2, Hayder Abdulhafedh Kurji3

1Medical Laboratory Technology Department, Bilad Al-Rafidain University College.2Medical Laboratory Technology Department, Erbil Polytechnic University,3Faculty of Pharmacy, Bilad Al-Rafidain University College.

Published

2020-04-29

How to Cite

Fatimah Kadhim Ibrahim AL- Mahdawi1, Zaid Nabeel Elia2, Hayder Abdulhafedh Kurji3. (2020). Evaluation Inhibin B, FSH, and LH in Male with Thalassemia. Indian Journal of Forensic Medicine & Toxicology, 14(2), 2437-2440. https://doi.org/10.37506/ijfmt.v14i2.3401