Synthesis and Characterization of Some Bis-Nitroaryl Pyrazolonesand Estimation of Their Anti-Bacterial and Anti-Fungal Activities

Authors

  • MuathJabbarTarfa Al-Abbasee1, Hamid J. Mohammad2, Mawlood K. Mawlood1

Keywords:

pyrazolone, one-pot synthesis, nitroaldehyde, antibacterial activity, antifungi activity.

Abstract

A simple and efficient one-pot synthesis of bicyclic nitro pyrazolone derivatives in traditional alcoholic solvents under refluxing conditions, The chemical structure of the synthesized derivatives was substantiated byFT-IR,1H NMR ,13C-NMRand CHNS analysis, All of these compounds of the series have been testedin vitro asantibacterial and antifungalagents against four types of organisms. The minimum and maximum inhibitory concentrations were determined against each organism.

Author Biography

MuathJabbarTarfa Al-Abbasee1, Hamid J. Mohammad2, Mawlood K. Mawlood1

1Chemistry Department, College of Education, University of Samarra, Iraq, 2Chemistry Department,
College of Applied Sciences, University of Samarra, Iraq

Published

2020-01-16

How to Cite

MuathJabbarTarfa Al-Abbasee1, Hamid J. Mohammad2, Mawlood K. Mawlood1. (2020). Synthesis and Characterization of Some Bis-Nitroaryl Pyrazolonesand Estimation of Their Anti-Bacterial and Anti-Fungal Activities. Indian Journal of Forensic Medicine & Toxicology, 14(1), 303-309. Retrieved from http://medicopublication.com/index.php/ijfmt/article/view/61