Hyperlipidemia that Induced in Male Rats and Role of Flavonoids Extract of Quercus infectoria in Treatment

Authors

  • Marwa Amer Shakir1, Iman Nozad Mahmood1

Keywords:

Quercus infectoria; hyperlipidemia; HMG-raductase

Abstract

The aim of the study demonstrates flavonoids of Quercus infectoria as anti-hyperlipidemia. 20 adult male rats used and divided to four equal groups (each group consist 5 rats); rats received ad libidium, rats were given normal water containing 0.5% of hydrogen peroxide and 1% of cholesterol in the feed for 60 days for induction of hyperlipidemia. Hyperlipidemia rats treated with (50mg/kg/daily) flavonoids, fourth Hyperlipidemia rats treated with (100mg/kg/daily) flavonoids. The results show non-significant changes (P < 0.05) in levels of HMG-raductase compare with control group. in hyperlipidemia rats, levels of malonedialdehyied (MDA) show significant increase (P < 0.05) in and significant decrease (P < 0.05) in levels of glutathione (GSH) and catalase compare with control group. While, after using flavonoids extract in treatment, the results showed non-significant changes (P < 0.05) in HMG-raductase, MDA, GSH and catalase compare with control group. It was concluded that flavonoids extract of Q. infectoria extract has been a protective effect in rats with hyperlipidemia.

Author Biography

Marwa Amer Shakir1, Iman Nozad Mahmood1

1Medical Laboratory Department/University of Al-Qalam College, IRAQ

Published

2020-01-16

How to Cite

Marwa Amer Shakir1, Iman Nozad Mahmood1. (2020). Hyperlipidemia that Induced in Male Rats and Role of Flavonoids Extract of Quercus infectoria in Treatment. Indian Journal of Forensic Medicine & Toxicology, 14(1), 510-513. Retrieved from http://medicopublication.com/index.php/ijfmt/article/view/98