Liver, Kidney Function Enzymes and Biochemical Parameters Evaluation for Hepatitis B and C in Iraqi Patients

Authors

  • Asmaa A. Hussein1, Ruqaya M. Al-Ezzy1, Raghad A. Ibrahim2

DOI:

https://doi.org/10.37506/ijphrd.v11i9.11021

Keywords:

Iraqi patients; Hepatitis B and C; kidney Function Enzymes; Health

Abstract

Hepatitis is inflammation of the liver tissue. Hepatitis is acute if it resolves within six months, and chronic
if it lasts longer than six months. Acute hepatitis can resolve on its own, progress to chronic hepatitis, or
(rarely) result in acute liver failure. Chronic hepatitis may progress to scarring of the liver (cirrhosis), liver
failure, and liver cancer. As hepatitis B and C are transmitted through blood and multiple bodily fluids,
prevention is aimed at screening blood prior to transfusion, abstaining from the use of injection drugs,
safe needle and sharps practices in healthcare settings, and safe sex practices.This study aimed to assess
the liver function enzyme and other biochemical test in Iraqi patients infected with Hepatitis B and C in
addition to patient treated with silymarin drug. The results showed the ability of silymarin drug to decrease
the elevated liver enzyme level of hepatitis B (137.52±5.71 vs. 350.19±2.15, 196.70±9.10 vs. 210.33±29.43
and 76.63±4.30 vs. 178.12±23.50)(U\L) for ALP, GPT and GOT respectively. The results of biochemical test
matches the results of liver enzymes throught decreasing the level of treated patints (42.50±3.37, 1.13±0.06
and 2.81±0.68) (mg\dL) in compared to hepatitis patiens (66.01±1.7, 2.28±0.20and 5.16±0.28) (mg\dL)
for blood urea, creatinin and total bilurbin respectively. The results indicated that hepatitis C patients
suffred from elevated liver enzymes level compared to treated humans (347.41±2.15 vs. 207.25±11.94,
256.07±29.43 vs. 137.61±2.186 and 167.6±4 vs. 95.2±4.7Unit/L) or healthy humans(64.89±25.01,
39.43±12.10 and 35.56±12.59) U\L for ALP, GPT and GOT respectively and the biochemical test agreed
with the previous results in which the level of treated humans decrease after treatment with silymarin in
compaired to elevated level for hepatitis patients(42.01±3.72 vs. 66.01±1.70, 1.33±0.13 vs. 2.280±0.2 and
1.60±0.11 vs. 4.16±0.28) mg\dL for for blood urea, creatinin and total bilurbin respectively.

Author Biography

  • Asmaa A. Hussein1, Ruqaya M. Al-Ezzy1, Raghad A. Ibrahim2

    1Assist. Prpf. Researcher,, College of Biotechnology, Al-Nahrain University, Baghdad, Iraq

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Published

2020-09-11

How to Cite

Liver, Kidney Function Enzymes and Biochemical Parameters Evaluation for Hepatitis B and C in Iraqi Patients. (2020). Indian Journal of Public Health Research & Development, 11(9), 276-281. https://doi.org/10.37506/ijphrd.v11i9.11021