To Determine the Safety and Efficacy of Transdermal Nitroglycerine Patch as Shortterm Tocolytic in Preterm Labor

Authors

  • G Pooja1 , B S Dhananjaya2 , K Omkara Murthy3

DOI:

https://doi.org/10.37506/ijphrd.v11i10.11133

Keywords:

Preterm labor, nitroglycerine patch, prolongation of pregnancy, side effects

Abstract

Background and Objectives: Preterm labour complicates 5-10% of pregnancies and is a leading cause
of neonatal morbidity and mortality worldwide. It is a major public health problem in terms of loss of life,
long-term disability (cerebral palsy, blindness, deafness, chronic lung disease) and health care costs both in
the developing and the developed world.
There is need for tocolytic therapy to reduce perinatal mortality and morbidity by delaying delivery at least
for 48 hours to allow time for therapeutic effects of corticosteroids
Methodology : This study was undertaken at Sri Siddhartha medical college and hospital research centre
tumakuru between October 2017 to October 2019.
76 Antenatal cases with gestational age 28weeks-37weeks as per the inclusion and exclusion criteria’s who
were admitted and clinically diagnosed as preterm labour were selected . The selected patients were treated
with Nitro-glycerine patch
Results : Success rate for acute tocolysis was 88.2%.Mean prolongation of pregnancy was 14.46 days and
mean birth weight of babies was 2.19 kilograms. Most common side effect with Nitroglycerine patch was
headache (5.3%).
Conclusion: Nitroglycerine patch is effective in suppression of preterm labor as short term tocolytic in
prolongation of pregnancy. Nitroglycerine is well tolerated and safe for the mother and fetus with minor
side effects

Author Biography

G Pooja1 , B S Dhananjaya2 , K Omkara Murthy3

1
Postgraduate Trainee, 2Professor and Head of the Department, 3Professor, Department of Obstetrics and
Gynaecology, Sri Siddartha Medical College and Hospital, Sri Siddhartha Academy of Higher Education (SSAHE),
Tumkur

Published

2020-10-06

How to Cite

G Pooja1 , B S Dhananjaya2 , K Omkara Murthy3. (2020). To Determine the Safety and Efficacy of Transdermal Nitroglycerine Patch as Shortterm Tocolytic in Preterm Labor. Indian Journal of Public Health Research & Development, 11(10), 161-165. https://doi.org/10.37506/ijphrd.v11i10.11133