Both ADC and rADC Average Rates in Hyperacute are Lower than those in Acute Stroke
Keywords:DWI, ADC average value, rADC, hyperacute stroke, acute stroke
Background: Radiology holds an important role in evaluating patients with suspected stroke. It is
therefore important to distinguish hyperacute or acute. DWI-ADC is an important modality. For ADC value
measurement, it is more accurate to use multiple b value. There is a significant variability of ADC values in
MRI depending on the coil system, imager, vendor, magnetic field strength and multicentre. The purpose of
the study is to find out the difference of ADC value in hyperacute and acute stroke. Analytical observational
study with cross sectional study approach to determine ADC values differences in Saiful Anwar Hospital
Malang. Head MRI of 3T with 3 b values (0, 500, 1000) was performed on every subject. The data were
analysed using descriptive statistic.
Results: There were 12 subjects observed, 6 in the hyperacute group (onset <24 hours) and acute (onset 24
hours - 1 week). There was a significant difference with p<0.05 on average ADC (10-3 mm2
/s) and rADC
(%) values between the hyperacute and acute groups. The ADC average mean ±SD of hyperacute (0.23 ±
0.05) was lower than acute (0.37 ± 0.04), and so as the ±SD rADC mean value of hyperacute (32 ± 8.1) was
less than acute (52 ± 4.3).
Conclusion: The ADC and rADC average values in the hyperacute were lower than that in the acute group.