Association of Patient Characteristics with in Vitro Fertilization (IVF) Failure in Graha Amerta Fertility Clinic Dr. Soetomo General Hospital, Surabaya

Abstract

Background : Due to the development of science and technology in the field of medicine, infertility has
been solved by the discovery of one of the most sophisticated ART program, known as IVF. Although this
procedure has been carried out for more than 40 years, the failure rate is still very high. This problem is
considered to be related with the characteristic of the patient undergoing IVF. This study aims to determine
the association between patient’s multi-characteristics and IVF failure.
Method : This research is an observational analytic research with cross-sectional method. The determination
of the research sample uses a total sampling technique by taking all members of the population in accordance
with the conditions.
Result : Out of 102 couples undergoing IVF, 37 couples (36,3%) successfully obtained a pregnancy while
the 65 other couples (63,7%) failed IVF or has not obtained a pregnancy. The result of the p value between
IVF failure and maternal age is 0,03, with BMI 0,532, with sperm quality 0,577, with PCOS 0,297, with
endometriosis 0,578, and with POR 0,027.
Conclusion : Out of all the studied patient characteristics, only maternal age and POR are associated with
IVF failure with the p value of 0,03 and 0,027 respectively. BMI, sperm quality, PCOS, and endometriosis
do not show a significant correlation with IVF failure.