Role of Interleukin 33 During Infection with Toxoplasmosis in Rheumatoid Arthritis Patients

Authors

  • Israa Kasim Al-Aubaidi1, Marwa Ali Al- Oqaily1, Sadia Shahab Hamad2

DOI:

https://doi.org/10.37506/ijfmt.v14i1.101

Keywords:

Toxoplasmosis , Rheumatoid arthritis, IgG , IgM , IL-33.

Abstract

Toxoplasma gondii is avery common obligate intercellular parasite with highest infection rate among worlds populations. The Rheumatoid arthritis (RA) considered as an autoimmune disease characterized by loss immunological tolerance to self-antigens. Present study Aims to detection the seroprevalence of toxoplasmosis among RA patients and healthy control and evaluate concentrations of IL-33 to understand their role during infection. Seropositive cases of IgG was 36.7% percentage in RA patients with highest value of IgG 0.395 IU/ml while control group was 100% seronegative. Three cases only were seropositive to IgM with 1.17% and their mean 0.54 IU/ml.
IL-33 levels in RA patients with toxoplasmosis was highest 187.74± 33.24 pg/ml when compared with RA patients 107.88±18.41 pg/ml and control group 55.59±25.75 pg/ml ,there was a significant differences in comparison between studied groups.

Author Biography

Israa Kasim Al-Aubaidi1, Marwa Ali Al- Oqaily1, Sadia Shahab Hamad2

1Biology Department, College of Eductation ( Ibn- Al- Haitham), University of Baghdad,Baghdad, Iraq, 2Biology Department , College of Science, Kirkuk University, Kirkuk, Iraq

Downloads

Published

2020-01-16

How to Cite

Israa Kasim Al-Aubaidi1, Marwa Ali Al- Oqaily1, Sadia Shahab Hamad2. (2020). Role of Interleukin 33 During Infection with Toxoplasmosis in Rheumatoid Arthritis Patients. Indian Journal of Forensic Medicine & Toxicology, 14(1), 526–531. https://doi.org/10.37506/ijfmt.v14i1.101

Issue

Vol. 14 No. 1 (2020): Indian Journal of Forensic Medicine & Toxicology

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Re use and mixing of content policy- We follow Creative Commons Licence Policy. We follow CC BY. Please refer below for all details

https://creativecommons.org/licenses/

CC BY

This license lets others distribute, remix, adapt, and build upon our work, even commercially, as long as they credit us for the original creation.

  1. The journal allows readers to read, download, copy, distribute, print, search, or link to the full texts of its articles and allow readers to use them for any other lawful purpose.
  1. The journal allows the author(s) to hold the copyright without restrictions.
  1. The journal allows the author(s) to retain publishing rights without restrictions