Examining The Forensic Toxicity of Ricin Using Lc/Ms Techniques
Keywords:Ricin; Chromatography; Peptide; Castor Bean; Protein; Toxin Peptide; Liquid Chromatography; RCA120; Mass Spectrometric.
As one the naturally occurring toxins, Ricin is classified among the deadliest poisons available. Ricin and
Ricinus communis agglutinin (RCA120) are derived from the castor bean plant. Ricin and its related activities
can be detected using either mass spectrometric (MS) assay or Liquid Chromatography (LC). Further, the
two methods can be to differentiate ricin from RCA120 because it is less toxic of the two. The sequence of
Amino acid is identified by monitoring the active ricin using mass spectrometric. This study discusses how
LC and MS methods can be applied to quantify, detect, and differentiate ricin from RCA120 in test samples.
On the overall, the two methods were applied to tell aside ricin samples from RCA120. The study concluded
that mass spectrometry is the most efficient approach in identifying ricin from RCA120.
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