Relationship of Sex Hormon Binding Globulin, Thyroid Stimulating Hormone, Testosterone and Prolactine with Body Mass Index (BMI) Value among Iraqi Females in Reproductive Age

Authors

  • Abbas Mehsen Gata1 , Jaleel Samanje2 , Ammer Abd. Mohammed1, Saman Jumaah3

DOI:

https://doi.org/10.37506/ijfmt.v14i3.10611

Keywords:

Iraq; Sex hormone binding globulin, Testosterone; obesity.

Abstract

Background: The purpose of this study was to determine the relation between increasing in the body mass

index (BMI) value and sex hormones level represented by sex hormon binding globulin (SHBG), Thyroid

stimulating hormone (TSH), testosterone and prolactine in 51 women in reproductive age aiming following

the life quality of these females.

Method: Participants were 51 women from center of Baghdad city. Every female full a questionnaire and

sex hormone concentration from each female were measured. Level of FBS and HbA1c test was estimated

and designed as exclusion criteria for diabetic mellitus and other metabolic disorders. Body mass index

value was compared by demographic properties, Pearson’s correlation coefficient and A stepwise method in

linear regression statistic test was applied to detect the association of BMI (kg/m2) with serum sex hormon

binding globulin (SHBG), Thyroid stimulating hormone (TSH), testosterone and prolactine and predict the

most affected factor.

Results: The mean and standard deviation level of most studied parameter were not differences between

case study and control females group (obese vs non-obese) in compared with normal value of each test. BMI

value were negatively correlated with age and SHBG (nmol/l) level (r = 0.156; P= 0.274) and (r = 0.578; P

= 0.00) respectively. While BMI were moderately positive correlated with testosterone (nmol/l), TSH (?IU/

mL) and prolactin (ng/ml) (r = 0.388; P = 0.005), (0.354; P = 0.011) and (0.37; P = 0.006) respectively.

Depending on the stepwise method in linear regression analyses, the SHBG (nmol/l) and testosterone

(nmol/l) were the most independent predictor factors for BMI in the studied groups (? = 0,484; P = 0.001)

and (? = 0.348; P = 0.001) respectively.

Conclusions: The most factors affecting obesity identified in the study were SHBG, Testosterone. However,

other variables such as age, did not impact the BMI value of participants.

Author Biography

  • Abbas Mehsen Gata1 , Jaleel Samanje2 , Ammer Abd. Mohammed1, Saman Jumaah3

    1 Lecturer, 2Dr. Lecturer, Middle Technical University, College of Health and Medical Technology / Baghdad, Iraq,

    3 M.Sc. Medical Biochemistry, Kirkuk health directorate, Kirkuk, Iraq

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Published

2020-07-30

How to Cite

Relationship of Sex Hormon Binding Globulin, Thyroid Stimulating Hormone, Testosterone and Prolactine with Body Mass Index (BMI) Value among Iraqi Females in Reproductive Age. (2020). Indian Journal of Forensic Medicine & Toxicology, 14(3), 1447-1453. https://doi.org/10.37506/ijfmt.v14i3.10611