Antibiotic Sensitivity of Streptococcus Pneumoniae that Isolated from Different Pneumococcal Infections
Keywords:Streptococcus pneumoniae, pneumonia, otitis media, antibiotic sensitivity
During the period from June of 2018 to February 2019 (150) isolates of Streptococcus pneumoniae were
isolated from 600 patients with clinical symptoms of Lower respiratory tract infections (LRTI) (pneumonia),
otitis media and meningitis obtained from Baqubah Hospitals. The results showed that not only S. pneumoniae
causes pneumonia and it can causes diseases other than pneumonia such as otitis media and meningitis
but with less frequency. S. pneumoniae showed different susceptibilities towards antibiotics used in this
study. The total susceptibility was (65.8%) and the total resistance was (34.2%). The highest pneumococcal
susceptibility was showed to the cell wall inhibitors (44.4%) followed by protein synthesis inhibitors (28%)
and quinolones (17.3%), and the lowest susceptibility was to folate antagonists with 0%. The highest rates
of susceptibility was to penicillin (100%), chloramphenicol (86%), vancomycin (80%) and moderate rates
of susceptibility to levofloxacin (90) 60%, linezolid (42.7) %, cefotaxime (40%), ofloxacin (40%) whereas
there was a relatively lower susceptibility rate towards other antibiotics such as ampicillin, imipenem,
amoxicillin, trimethoprim/sulfamethoxazole. Therefore, it should be avoided in the treatment in addition to
tazobactam, amikacin, gentamicin, which had lowest rates susceptibility against S. pneumoniae. As a result,
it required more research to identify new antibiotic or vaccine to reduce the risk of pneumococcal infection.
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