Correlation between Urinary Bisphenol A (BPA) Levels and Male Reproductive Functions among Sample of Egyptian Population
Keywords:Bisphenol A (BPA); Endocrine disruptors; Male infertility; Sperm functions; Xenoestrogens
BPA as a xenoestrogen negatively influences male reproductive functions as well as sperm quality. This
study aimed at evaluating the correlation between urinary BPA concentrations and male fertility by assessing
semen parameters as well as hormone profile. It included (150) males divided into two groups; infertile cases
(n= 100) and fertile controls (n= 50). Results showed highly significant difference in mean urinary BPA
concentrations between both groups being higher among infertile group (P-value < 0.001). Besides that,
there was statistically significant correlation between the mean urinary BPA concentrations and deterioration
of sperm concentration and motility among cases with P-values (< 0.001). Finally, there was statistically
significant correlation between mean urinary BPA and hormone levels FSH, LH, T and E2 levels with
P-values 0.002, 0.033, 0.001 and < 0.001 respectively.
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