Detection Antibodies IgM, IgG and Determination Levels of IL-33 in Iraqi Diabetic Type 2 Patients Infected with Toxoplasma Gondii
Keywords:Toxoplasma gondii, IgM, IgG, Diabetes mellitus type 2, IL-33.
Toxoplasma gondii is an obligate intracellular protozoan that causes a disease called toxoplasmosis which
has the capability to pass its both life cycle parts asexual and sexual in the final host (cats)and also through
intermediate vertebrate hosts including humans. Diabetes mellitus is a metabolic disorder that there is high
blood sugar level over a prolonged period. This research included one hundred and twenty blood samples
that collected from diabetic patients after diagnosing them by endocrinologist at the Imamein Kadhimein
Medical City during August until the end of December 2016 with age ranging 12-76 years with mean 50.9
± 13.8. Toxoplasmosis diagnoses was occurred by using Toxo IgG and IgM antibodies immulite torch assay
while diabetes diagnosis by fasting blood sugar tests also measuring level of IL-33 in samples was done
by sandwich ELISA method that showed a group of diabetic patients infected with toxoplasmosis have
the highest level of IL-33. The results showed that a group of diabetic patients have the highest level of
glucose in diabetes test (188.31 pg/ml)while a group of diabetic patients infected with toxoplasmosis have
the highest level of IgG (106.17 IU/ml)while all samples have seronegative results for Toxo IgMalso the
highest level of IL-33 showed ina group of diabetic patients infected with toxoplasmosis (858.84 pg/ml)
while a group of diabetic patients not infected with toxoplasmosis have (556.67 pg/ml) and control group
How to Cite
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Re use and mixing of content policy- We follow Creative Commons Licence Policy. We follow CC BY. Please refer below for all details
This license lets others distribute, remix, adapt, and build upon our work, even commercially, as long as they credit us for the original creation.
- The journal allows readers to read, download, copy, distribute, print, search, or link to the full texts of its articles and allow readers to use them for any other lawful purpose.
- The journal allows the author(s) to hold the copyright without restrictions.
- The journal allows the author(s) to retain publishing rights without restrictions