Oral Care Colostrum Effect on Preterm Infants Fecal Immunoglobulin A Secretory Level

Abstract

Objective To evaluate whether oral care colostrum can increase fecal secretory immunoglobulin A levels in
preterm infants.
Methods Thirty-eight infants who met the inclusion criteria were randomized. Twenty colostrum oral care
infants and eighteen control control infants. Colostrum oral care by giving as much as 0.1 ml of colostrum
on each buccal mucosa for approximately 2 minutes on one side. The procedure is repeated every 4 hours
for 3 days. Fecal secretory immunoglobulin A levels are taken from the first faecal after birth and 72 hours
after colostrum administration. Fecal retrieval must first install a urine device so that the urine does not wet
the sample.
Result Fecal secretory immunoglobulin A level before treatment in the treatment group were 0.0633 ±
0.0037 mg/g feces higher than the control group 0.0166 ± 0.0139 mg/g feces, statistically there were no
significant differences (p = 0.595). Fecal secretory immunoglobulin A level after treatment in the treatment
group amounted to 1,1007 ± 0.2458 mg/g feces higher than the control group 0.6045 ± 0.2358 mg/g faeces,
statistically there were no significant differences (p = 0.09 ). Difference in increase in secretory fecal
immunoglobulin A levels after and before treatment in the treatment group 1.0374 ± 0.2575 mg/g feces is
higher than the control group 0.5879 ± 0.2385 mg/g feces, statistically there were no significant differences
(p = 0.09).
Conclusion Oral care colostrum has been shown to increase secretory immunoglobulin A levels in preterm
infants before colostrum oral care, and colostrum oral care has the potential to increase faecal secretory
immunoglobulin A level than controls in preterm infants.