Role of AgNORs in Oral Lesions-A Review

Authors

  • R.Hariharan1 , N.Anitha2 , E.Rajesh2 , AravindhaBabu3

DOI:

https://doi.org/10.37506/ijfmt.v14i4.11711

Keywords:

Nucleolar organizer regions, NOR-associated proteins, Argyrophilic nucleolar organizer regions, proliferative activity, AgNOR dots, quantitative, qualitative.

Abstract

The biologic behavior of the oral lesions can be determined by their active phases of cell division, cells
entering the cell cycle and their proliferation. AgNORs (argyrophilic nucleolar organizer regions) staining
is the one of the cytochemical technique used to evaluate the cell proliferation of oral lesions. Tumor cells
in premalignant and malignant conditions usually exhibits a rise in synthesis of abnormal proteins and
proportionately there is a increase in the AgNOR material. The aim of this study was to review the concepts
of proliferative activity of cells of malignant and premalignant conditions through the AgNORs staining
procedure and thereby proving the usefulness of AgNORs in diagnosing the oral lesions.

Author Biography

  • R.Hariharan1 , N.Anitha2 , E.Rajesh2 , AravindhaBabu3

    1
    Post graduate Student, 2Reader, 3Professor, Department of Oral Pathology and Microbiology, Sree Balaji Dental
    College and Hospital, Bharath Institute of Higher Education and Research
    Department of Oral Pathology and Microbiology, Sree Balaji Dental College and Hospital, Bharath Institute of
    Higher Education and Research, Pallikaranai, Chennai

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Published

2020-10-29

Issue

Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology

Section

Articles

License

https://creativecommons.org/licenses/by-nc/2.0/deed.en

How to Cite

Role of AgNORs in Oral Lesions-A Review . (2020). Indian Journal of Forensic Medicine & Toxicology, 14(4), 1321-1324. https://doi.org/10.37506/ijfmt.v14i4.11711