Bone Morphogenetic Protein-1 and Its Regulation - A Review

Authors

  • Niha Naveed1 , Kishorekumar S2

DOI:

https://doi.org/10.37506/ijfmt.v14i4.11736

Keywords:

BMP1, TGF ?-1, lysyl oxidase, SpAN, bone, growth, cartilage

Abstract

Bone morphogenetic protein 1, also referred to as BMP1, is a protein encoded by the BMP1 gene in humans.
There are seven protein isoforms created through alternative splicing.It leaves the C-terminal propeptides
of procollagen I, II and III. It induces cartilage and bone formation. It may participate in dorsoventral
patterning during early development by cleaving chordin (CHRD). It is also responsible for the proteolytic
activation of lysyl oxidase LOX.

Author Biography

  • Niha Naveed1 , Kishorekumar S2

    Post graduate Student, 2Professor, Department of Orthodontics and Dentofacial Orthopedics, Sree Balaji Dental
    College & Hospital

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Published

2020-10-29

Issue

Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology

Section

Articles

License

https://creativecommons.org/licenses/by-nc/2.0/deed.en

How to Cite

Bone Morphogenetic Protein-1 and Its Regulation - A Review. (2020). Indian Journal of Forensic Medicine & Toxicology, 14(4), 1427-1430. https://doi.org/10.37506/ijfmt.v14i4.11736