Recent Advances in Cytology-A Review

Abstract

In olden days, specificity and sensitivity of oral cytology is poor. Utilizing traditional oral cytology for the
conclusive diagnosis of malignancyand premalignant lesions. But with the recent cytological techniques
paves cytology to conclude a final diagnosis. This reestablished interest is somewhat because of the
presentation of a specific brush that gathers a full-thickness epithelial sample and not simply sloughed cells,
just as examination of that sample with computer support and analysis. There is an assortment of adjunctive
strategies have been acquainted with possibly upgrade the finding of the cytologic examples including DNA
examination, immunocytochemistry, molecular analysis, and liquid based preparations. An expansion in
sensitivity (>96%) and specificity (>90%) of the oral brush biopsy with computer support, diagnosis has
been accounted for detection of malignant and premalignant lesions. Brush cytology is significant to forestall
misdiagnosing suspicious oral lesions.