Activity of Extract Seed Moringa Oleifera on Gene Expression of (EFB1) Gene in Candida dubliniensis Isolated from oral Candidiasis to Cancer Patients

Authors

  • Zahraa Khudhair Abbas Al-Khafaji1 Farqad Abdulelah Ali AL-Janahi2 , Al-karrar Kais abdul Jaleel Duaibel3

DOI:

https://doi.org/10.37506/ijfmt.v14i4.11768

Keywords:

Moringa oleifera, (EFB1) Gene elongation factor 1-beta Candida dubliniensis , Candidiasis.

Abstract

Gene expression of EFB1 gene in yeast Candida dubliniensis isolated from oral candidiasis in cancer
patients was detected using by R-time PCR for some isolates before and during the yeast infection of the
epithelial cells. The results showed a high rate of gene expression of T2 ( 42.104 ± 6.533) and a significant
difference at the probability level P>0.01 compared with the treatment was c (1.034 ± 0.126 ) and the use
of the Moringa oleifera extract was 25% to evaluate its effect on the gene expression (ALS1) before and
during yeast infection of epithelial cells. The results showed that the gene expression of T1 was decreased
by ( 0.129 ± 0.021) compared to (C) value (1.034 ± 0.126) .
As for the T2 treatment was gene expression at a rate (42.104 ± 6.533) high Compared with T3 treatment in
which gene expression dropped at a rate (22.143 ± 4.176 ) and with a significant difference at the level of
the probability of P ? 0.01.

Author Biography

  • Zahraa Khudhair Abbas Al-Khafaji1 Farqad Abdulelah Ali AL-Janahi2 , Al-karrar Kais abdul Jaleel Duaibel3

    1
    Lecturer PhD, 2Assistant Lecturer, 3Assistant Lecturer. Islamic University, Clinical Laboratory Investigations
    Techniques, Najaf, Iraq

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Published

2020-10-29

How to Cite

Activity of Extract Seed Moringa Oleifera on Gene Expression of (EFB1) Gene in Candida dubliniensis Isolated from oral Candidiasis to Cancer Patients. (2020). Indian Journal of Forensic Medicine & Toxicology, 14(4), 1581-1587. https://doi.org/10.37506/ijfmt.v14i4.11768