Effect of Insecticide “Maxxthor” on Some Hematological and Oxidative Stress Parameters in Male Albino Rats

Abstract

The present study was designed to investigate the effect of different concentrations of Maxxthor on some
hematological and oxidative stress parameters in male albino rats.Twenty male rats with age of 6-8 weeks and
weight of 200-250gm were equally divided into four groups as follow:G1 treated with normal saline as control
group,while G2,G3andG4groups were treated with(0.01,0.1,1)mg\kg body weight of Maxxthor respectively
for 40 days.The following hematological parameters were measured: red blood cell(RBC),hemoglobin
(Hb),white blood cell(WBC), platelets(PLT),malondialdehyde(MDA),glutathione(GSH),catalase and
vitamin E. The hematological parameters results revealed highly significant(p<0.01)decreasein RBC and
H,while a highly significant(p<0.01)increase in WBC and PLT in all treated groups as compared with control.
The oxidative stress parameters results revealed highly significant(p<0.01)increase in MDA level,while
highly significant(p<0.01)decrease in GSH,catalase and vitamin E level were noticed in all treated groups
as compared with control .