The Cytotoxicity Effect for the Crude Extract of (Cyperus Esculentus) Tubers on Human Breast Cancer Cell Line (MCF-7) in Vitro

Abstract

The study aimed to identify the aqueous and alcoholic extract of Cyperus esculentus tubers in affecting
human breast cancer (MCF-7) Michigan Cancer Foundation,preliminary diagnosis chemical groups in these
extracts showed the presence of (Tannins, Terpenoids, Resins, Steroids, Flavonoids, Alkaloids, Glycosides
and Phenols). The effect of cellular toxicity of crude aqueous and alcoholic extract of Cyperus esculentus
tubers in vitro was tested in human breast cancer cells (MCF-7) through the use of six concentrations
(midterm scares) (31.25,62.5,125,250,500,1000 ) ?g /mL and for periods of exposure (24, 48, 72) hours.
Using the MTT Test. The study found that there is a toxic effect of the crude aqueous and alcoholic extracts
of the grain of Cyperus esculentus tubers in cancer cells (MCF-7) and of all the concentrations used, The
highest percentage and a significant difference (P ?0.01) for the average of the inhibitory average of cancer
cell growth (IR) was 68, 73 (%) for the aqueous extract and alcoholic extract, respectively, at the highest
concentration of 1000 ?g / mL and after 72 hours of exposure.