Evaluation of Salivary ?- Amylase Enzyme Activity in Smoker and Peptic Ulcer Patients affected by Periodontitis in Relation to Clinical Periodontal Parameters

Authors

  • Nada Kadhim Imran1 , Omar Husham Ali1 , Maha Abdulaziz Ahmed1

DOI:

https://doi.org/10.37506/ijfmt.v14i4.11939

Keywords:

periodontitis, diagnosis of PUD ; peptic ulcer, alpha-Amylases, toxicity;

Abstract

Objectives: To investigate the activity of salivary ?-amylase (SA) in subject affected by periodontitis alone
or associated with peptic ulcer disease (PUD) with or without smoking.
Methods: The study population was divided into control group (C), study groups; periodontitis (G1),
periodontitis+ PUD+ smokers (G2), periodontitis+ PUD+ nonsmoker (G3). The clinical periodontal
parameters including plaque index (PI), gingival index (GI), probing pocket depth (PPD), and clinical
attachment level (CAL) were recorded.
In addition, unstimulated whole saliva was collected from these
patients for analysis of SA level.
Results: Analysis showed that PI and GI showed significant difference among study groups versus controls.
G2 exhibited significantly higher PPD and CAL as compared with G1 but not with G3. For SA activity, G2
and G3 showed significantly higher activity as compared with C and G1 groups. Yet, no significant difference
was seen between C and G1 and between G2 and G3. Activity of SA was positively and significantly (P<
0.05) correlated with increasing PPD in all study groups and with CAL measurements of G2 only.
Conclusions: The results suggested that SA could be used as a marker for the diagnosis of PUD in subjects
affected by periodontitis with or without smoking.

Author Biography

  • Nada Kadhim Imran1 , Omar Husham Ali1 , Maha Abdulaziz Ahmed1

    Lecturer, Prof., Department of Periodontics, College of Dentistry, University of Baghdad/Iraq

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Published

2020-10-29

How to Cite

Evaluation of Salivary ?- Amylase Enzyme Activity in Smoker and Peptic Ulcer Patients affected by Periodontitis in Relation to Clinical Periodontal Parameters. (2020). Indian Journal of Forensic Medicine & Toxicology, 14(4), 2349-2355. https://doi.org/10.37506/ijfmt.v14i4.11939