Prevalence of Histopathological Diagnosis of Benign and Malignant Breast Lesions in Al-Muthanna Province for Two Years Duration

Abstract

Introduction: Breast cancer (BC) is a common form of cancer among women globally. It is considered 5th
cause of death in females with equally to 522,000 patients / year. Nowadays it is considered 15.4% of death
in developed countries after lung cancer. In developing nations, breast cancer considered the 1st cause of
death for females 324,000 cases of deaths (14.3%) for total deaths. Method: One hundred and six female
patients with breast lesion were collected from the Al-Hussein Teaching Hospital Laboratory/Histopathology
department –Al-Muthanna province, during the period from January 2018 to January 2020. The data for
cases were collected to study the age, type of breast lesion whether benign or malignant. Haematoxylin/
Eosin staining done in Al-Hussein Teaching Hospital Laboratory / Histopathology department. Results:
Cross sectional study for 106 patients done in Al- Muthanna proven for assessment breast mass and identify
malignant and benign lesion, mean age of patients was (39.4 ± 15.8) years old, with min age 13 years and
max age was 81 years old. Types of biopsy taken from surgeon were 71% excisional biopsy, 21% mastectomy
and 8% true cut biopsy. After pathological assessment of biopsies showed 51% malignant and 49% benign.
In addition, this assessment distributed as following: fibroadenoma 31.1%, IDC/ grade II 29.2%, IDC/ grade
III 9.4%, ILC and fibrocystic changes 5.7% and IDC grade I 3.8% and other types of malignant and benign
after pathological assessment. Significant association between age groups and cancer of breast. Conclusion:
After pathological assessment of biopsies, malignant breast cancer (IDC/ grade II, IDC/ grade III, ILC and
fibrocystic changes) most common changes, significant association between age group and breast cancer
development more age group 41- 50 years old and then (31- 40), (51– 60) years old respectively.