Blood Cells Depletion after Chemotherapy in Iraqi Women with Breast Cancer

Abstract

The research was aimed to study the effect of chemotherapy on white blood cells especially lymphocytes,
and the relationship between chemotherapy and red blood cells, platelets in women with breast cancer. Our
results showed that the mean ± SE of White Blood Cells (WBCs) and lymphocytes before treatment was
significantly higher than the mean ± SE of lymphocytes and WBCs after treatment at (P<0. 01), the mean
± SE of Red Blood Cells (RBCs) and platelets before treatment was higher than the mean ± SE of RBCs
and lymphocyte after treatment at (P<0. 01). The reason probably due to the poor nutrition and the effect of
cancer of the breast on erythropoiesis on the cases, or metastasis to the bone marrow from breast cancer can
be associated with suppression of blood cells synthesis. We concluded that chemotherapy for breast cancer
is in association with long-term changing in immune system parameters and other cells during clinical
management.